The IMGT/HLA database
Top Cited Papers
Open Access
- 11 November 2010
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 39 (Database) , D1171-D1176
- https://doi.org/10.1093/nar/gkq998
Abstract
It is 12 years since the IMGT/HLA database was first released, providing the HLA community with a searchable repository of highly curated HLA sequences. The HLA complex is located within the 6p21.3 region of human chromosome 6 and contains more than 220 genes of diverse function. Many of the genes encode proteins of the immune system and are highly polymorphic. The naming of these HLA genes and alleles and their quality control is the responsibility of the WHO Nomenclature Committee for Factors of the HLA System. Through the work of the HLA Informatics Group and in collaboration with the European Bioinformatics Institute, we are able to provide public access to this data through the web site http://www.ebi.ac.uk/imgt/hla/ . Regular updates to the web site ensure that new and confirmatory sequences are dispersed to the HLA community, and the wider research and clinical communities.Keywords
This publication has 28 references indexed in Scilit:
- A new bioinformatics analysis tools framework at EMBL-EBINucleic Acids Research, 2010
- Allele Name Translation Tool and Update NomenCLature: software tools for the automated translation of HLA allele names between successive nomenclaturesTissue Antigens, 2010
- Nomenclature for factors of the HLA system, 2010Tissue Antigens, 2010
- Improvements to services at the European Nucleotide ArchiveNucleic Acids Research, 2009
- DDBJ launches a new archive database with analytical tools for next-generation sequence dataNucleic Acids Research, 2009
- Web services at the European Bioinformatics Institute-2009Nucleic Acids Research, 2009
- The IMGT/HLA databaseNucleic Acids Research, 2008
- Gene map of the extended human MHCNature Reviews Genetics, 2004
- Basic Local Alignment Search ToolJournal of Molecular Biology, 1990
- Basic local alignment search toolJournal of Molecular Biology, 1990