EFFECT OF ENDOSULFAN ON BIOELECTRICAL ACTIVITY OF BRAIN IN RATS

1 January 1980

journal article
research article

Vol. 22 (6) , 385-387

Abstract

Bioelectrical activity of rat brain was studied after administration of endosulfan (5 mg/kg, i.p.) for 10 days. The insecticide produced rhythmic bursts of spikes and waves of seizure pattern that started 25-30 min after dosing and persisted for 60 min. The clonic convulsions were more marked over the head region and were mainly localized in the upper extremities. Histopathologic examination of the liver showed congestion of the central veins and its adjacent sinusoids. Concentration of the compound in brain paralleled the electrical activity.

This publication has 0 references indexed in Scilit: