Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy
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- 1 January 2001
- journal article
- Published by Taylor & Francis in Cancer Investigation
- Vol. 19 (4) , 424-436
- https://doi.org/10.1081/cnv-100103136
Abstract
Pegylated liposomal doxorubicin (Doxil, Caelyx) is a formulation of doxorubicin in poly(ethylene glycol)-coated (stealth) liposomes with a prolonged circulation time and unique toxicity profile. We...Keywords
This publication has 51 references indexed in Scilit:
- Phase I trial of doxil plus cisplatin (DDP) in patients (pt) with advanced malignanciesEuropean Journal Of Cancer, 1999
- Significant Increase in Antitumor Potency of Doxorubicin Hc1 by its Encapsulation in Pegylated LiposomesJournal of Liposome Research, 1999
- Long-circulating liposomes for drug delivery in cancer therapy: a review of biodistribution studies in tumor-bearing animalsAdvanced Drug Delivery Reviews, 1997
- Polyethylenglykol-umhülltes (pegyliertes) liposomales DoxorubicinDrugs, 1997
- ForewordHuman & Experimental Toxicology, 1996
- Liposome Longevity and Stability in Circulation: Effects on the in vivo Delivery to Tumors and Therapeutic Efficacy of Encapsulated AnthracyclinesJournal of Drug Targeting, 1996
- Doxorubicin Encapsulated in Liposomes Containing Surface‐Bound Polyethylene Glycol: Pharmacokinetics, Tumor Localization, and Safety in Patients with AIDS‐Related Kaposi's SarcomaThe Journal of Clinical Pharmacology, 1996
- Complement Activation in Rats by Liposomes and Liposome-Encapsulated Hemoglobin: Evidence for Anti-lipid Antibodies and Alternative Pathway ActivationBiochemical and Biophysical Research Communications, 1994
- Preclinical Studies with Doxorubicin Encapsulated in Polyethyleneglycol-Coated LiposomesJournal of Liposome Research, 1993
- Gelation of liposome interior A novel method for drug encapsulationFEBS Letters, 1992