THE INFLUENCE OF SODIUM NITRITE, PEPTONE AND PILOCARPINE ON THE EXTERNAL SECRETION OF THE PANCREAS

Publisher Website
Google Scholar
Abstract
Intravenous administration of NaNO2 or peptone results in a fall of blood pressure, due primarily to a splanchnic vasodilation,and an accelerated pancreatic secretion rate. The nitrite secretagogue action is probably the consequence of improved nutritional conditions, since cutting the vagi, ligation of the pylorus, administration of atropine or ergotamine, did not inhibit the reaction. Simultaneous administration of NaNO2 and Bayliss and Starling secretin resulted in a greater secretion than was obtainable from a double dose of either secretagogue alone. Pilocarpine accelerates the external pancreatic secretion rate through parasympathetic stimulation only.

This publication has 0 references indexed in Scilit: