Improved Procedure for Hypophysectomy of the Mouse.
- 1 October 1955
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 90 (1) , 267-269
- https://doi.org/10.3181/00379727-90-22004
Abstract
A practical procedure for mouse hypophysectomy by the parapharyngeal approach was developed. Innovations include tracheal cannulation, resuscitation in an O2 atmosphere, and hydrocortisone therapy. Mice of the A/He strain are particularly vulnerable to effects of pituitary loss and will survive only if supplied with an adrenal steroid at regular intervals. Mice of the C57BL,C3H, BALB/c and Swiss albino strains require no special postoperative handling.Keywords
This publication has 2 references indexed in Scilit:
- A TECHNIC FOR HYPOPHYSECTOMY OF THE MOUSE*Endocrinology, 1938
- Hypophysectomy and a replacement therapy in the ratJournal of Anatomy, 1930