Monoclonal antibody reactive with both p28 and p19 of adult T-cell leukemia virus-specific polypeptides.

  • 1 June 1983
    • journal article
    • Vol. 74  (3) , 327-30
Abstract
Mouse monoclonal antibodies, GIN-2, -7 and -14, against adult T-cell leukemia virus (ATLV) were prepared by a hybridoma procedure. These antibodies belonged to different subclasses of IgG, but they reacted similarly with both ATLV-specific polypeptides p19 and p28. In the reaction with monoclonal antibodies and various ATLV-producer cell lines, it was found that MT-2 and MT-2-related T-cell lines produced both p19 and p28, whereas MT-2-unrelated cell lines produced p19, but not p28.

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