The specificity of collagen cross-links as markers of bone and connective tissue degradation
Open Access
- 1 January 1995
- journal article
- research article
- Published by Taylor & Francis in Acta Orthopaedica
- Vol. 66 (sup266) , 166-170
- https://doi.org/10.3109/17453679509157685
Abstract
The availability of a specific and convenient biochemical assay for quantifying bone turnover would aid in the clinical management of osteoporosis and other metabolic bone diseases. Recently, several immunoassays for bone metabolites have been reported in the research literature, with data suggesting that certain of them may now have the required specificity and responsiveness to bone cell activity and convenience for routine clinical use.Keywords
This publication has 20 references indexed in Scilit:
- New markers of bone metabolism: clinical use in metabolic bone diseaseActa Endocrinologica, 1995
- Specificity of urinary excretion of cross-linked N-telopeptides of type I collagen as a marker of bone turnoverCalcified Tissue International, 1994
- Immunoassay for urinary pyridinoline: The new marker of bone resorptionJournal of Bone and Mineral Research, 1993
- Clinical use of biochemical markers of bone remodeling in osteoporosisBone, 1992
- A specific immunoassay for monitoring human bone resorption: Quantitation of type I collagen cross-linked N-telopeptides in urineJournal of Bone and Mineral Research, 1992
- Urinary pyridinium crosslinks of collagen Specific markers of bone resorption in metabolic bone diseaseTrends in Endocrinology & Metabolism, 1992
- Changes with age in the urinary excretion of lysyl- and hydroxylysylpyridinoline, two new markers of bone collagen turnoverJournal of Bone and Mineral Research, 1990
- Measurement of the cross linking compound, pyridinoline, in urine as an index of collagen degradation in joint disease.Annals of the Rheumatic Diseases, 1986
- CROSS-LINKING IN COLLAGEN AND ELASTINAnnual Review of Biochemistry, 1984
- An enzyme-linked immunoassay for the collagen cross-link pyridinolineBiochemical Journal, 1982