Thermodynamic study of dimethyltin(IV) complexes with nucleoside 5′-triphosphates

Abstract
The complex formation of [SnMe2]2+ ion with guanosine 5′-triphosphate (GTP), inosine 5′-triphosphate (ITP), cytidine 5′-triphosphate (CTP) and tripolyphosphate(5–)(tpp) has been investigated by means of potentiometric and calorimetric measurements at 25 °C and I= 0.1 mol dm–3(KNO3). On the basis of the thermodynamic parameters, bonding details have been inferred for the main nucleotide complex species, using tpp as reference. The thermodynamic data show that the nitrogen atom [N(1)] of the bases interacts with dimethyltin in the [SnMe2L] species of GTP and ITP only.

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