A Summary of Work on Aldrin and Dieldrin Toxicity at the Kettering Laboratory

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Abstract
The level of agricultural productivity in the USA depends upon the use of effective broad spectrum insecticides. Two of the most efficacious insecticides are aldrin and dieldrin. While these substances are highly toxic to insects and experimental animals, no definitive evidence is available that any harm has resulted to mankind. The incidence of tumors in male and female rats fed on diets containing aldrin and dieldrin for a period of 2 years was of the same order of magnitude as that observed in control animals. Thus, on this basis, aldrin and dieldrin are neither tumorigenic nor carcinogenic substances. Although it is essential to protect the health of the general public, t is equally essential that any decision to restrict the use of aldrin and dieldrin by enforcement agencies must be based on sound and factual data, first establishing that a hazard in reality exists.

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