Low-dose budesonide treatment for prevention of postoperative recurrence of Crohnʼs disease
- 1 March 1999
- journal article
- clinical trial
- Published by Wolters Kluwer Health in European Journal of Gastroenterology & Hepatology
- Vol. 11 (3) , 277-282
- https://doi.org/10.1097/00042737-199903000-00011
Abstract
Although the effect of budesonide was altogether positive in almost all variables studied in this train (e.g. endoscopic and histopathological score, time-to-failure, CDAI, patients' global judgement and rate of side effects), this increase in efficacy was small and the power for the detecting differences versus placebo was too low to be statistically significant. According to these results, low-dose oral budesonide cannot be recommended to be used for the prevention of postoperative relapse in Crohn's diseaseKeywords
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