Folate analogs. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds
- 1 June 1989
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 32 (6) , 1284-1289
- https://doi.org/10.1021/jm00126a023
Abstract
Note: In lieu of an abstract, this is the article's first page.This publication has 4 references indexed in Scilit:
- Folate analogs. 31. Synthesis of the reduced derivatives of 11-deazahomofolic acid, 10-methyl-11-deazahomofolic acid, and their evaluation as inhibitors of glycinamide ribonucleotide formyltransferaseJournal of Medicinal Chemistry, 1989
- ACTIVITY OF THE NEW ANTIFOLATE N-10-PROPARGYL-5,8-DIDEAZAFOLATE AND ITS POLYGLUTAMATES AGAINST HUMAN DIHYDROFOLATE-REDUCTASE, HUMAN THYMIDYLATE SYNTHETASE, AND KB CELLS CONTAINING DIFFERENT LEVELS OF DIHYDROFOLATE-REDUCTASE1985
- TREATMENT OF REUBER H35 HEPATOMA-CELLS WITH CARRIER-BOUND METHOTREXATE1981
- A potent antitumour quinazoline inhibitor of thymidylate synthetase: Synthesis, biological properties and therapeutic results in micePublished by Elsevier ,1981