Total colectomy and the cancer family syndrome

Abstract
A case is reported of a 47-year-old man with a family history consistent with Cancer Family Syndrome (CFS), who manifested proximal colon carcinoma. On the authors' recommendation, with the knowledge that the colon in CFS shows an inordinate lifelong susceptibility to malignant neoplastic transformation, a total abdominal colectomy was performed. The resected colon was found to contain an additional occult carcinoma distal to the primary lesion. Knowledge of this phenomena is critical to the management of CFS

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