Lymphocytes in Patients With Ovarian Cancer
- 1 June 1975
- journal article
- lymphocytes in-patients-with-ovarian-cancer
- Published by Wolters Kluwer Health in Obstetrics & Gynecology
- Vol. 45 (6) , 656-668
- https://doi.org/10.1097/00006250-197506000-00011
Abstract
Studies to determine the total number of circulating lymphocytes and their morphologic transformation in the presence of phytohemagglutinin and pokeweed mitogen were carried out in 156 women: 81 who currently had an ovarian cancer or who had had it in the past; 54 normal women; and 21 patients with malignant diseases. The latter two groups served as controls. The total number of circulating lymphocytes is an important consideration, as there is a significant decrease of lymphocytes in patients with ovarian cancer, a factor with great bearing on prognosis. The lymphoblastic transformation test in the presence of phytohemagglutinin and pokeweed mitogen showed not only significant changes in patients with ovarian cancer but also a correlation with survival at 6 months.Keywords
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