Angiolymphoid Hyperplasia With Eosinophilia (Kimura's Disease)

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Abstract
• A 28-year-old man with slight blood eosinophilia had multiple dermal lesions of angiolymphoid hyperplasia with eosinophilia in the right knee region. A fistula between the popliteal artery and vein was demonstrated by arteriography. Between the tortuous blood vessels composing this shunt, an inflammatory reaction similar to that found in the superficial lesions was seen. A few vascular branches showed arteritis. In both the superficial and deeper lesions, some blood vessels, including the popliteal artery and vein, showed intravascular angiomatosis. Ten months after surgery, the patient had asthma with notable blood eosinophilia and increased serum IgE levels without demonstrable allergens. The possible relationship between these findings is presented. (Arch Dermatol 1981;117:650-653)