An Improved Procedure forN-Formylation of Secondary Amines Using Chlorotrimethylsilane-Imidazole-N,N-Dimethylformamide
- 1 January 1992
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1992 (08) , 659-660
- https://doi.org/10.1055/s-1992-21448
Abstract
An improved method for the N-formylation of secondary amines using chlorotrimethylsilane and imidazole in N,N-dimethylformamide is described. The reaction conditions are tolerant of ester functional groups, and an amine hydrochloride may be N-formylated using a slight modification of the procedure.Keywords
This publication has 0 references indexed in Scilit: