Species Distribution and Antibiotic Sensitivity of Bacteria Isolated Pre- and Postoperatively from Patients Undergoing Transurethral Prostatic Resection
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Urology and Nephrology
- Vol. 18 (3) , 187-192
- https://doi.org/10.3109/00365598409180182
Abstract
The identity and antibiotic sensitivity of the isolated bacteria from 179 patients undergoing transurethral resection of the prostate were analysed. The patients were randomized into a group receiving a short course of cefotaxime in conjunction with the operation and a control group given no antibiotics. Preoperatively 70 patients had bacteriuria (≥107 CFU/I) with a predominance of Gram-negative bacteria (57 isolates, mainly Escherichia coli, Enterobacter, Klebsiella ssp. Proteus sspl. although Gram-positive species (24 isolates, mainly enterococci and Staphylococcus epidermidis) were also frequently encountered. Preoperatively isolated pathogens were evenly distributed in both groups and the sensitivity pattern was comparable. In the cefotaxime group postoperative recurrence of the preoperatively identified bacteria occurred in a lower frequency (11/43) than persistence in the control group (24/38). Only Gram-negative pathogens were isolated from patients with postoperative septicemia and upper urinary tract infections indicating that it is most important to direct prophylaxis against Gram-negative bacteria. A high degree of sensitivity against cefotaxime, gentamicin, trimethoprim, co-trimazine and a combination of ampicillin and mecillinam was recorded among both pre- and postoperatively isolated bacteria.Keywords
This publication has 17 references indexed in Scilit:
- A NEW MEDIUM FOR THE BACTERIOLOGIC EXAMINATION OF STOOLS (LSU-AGAR)Acta Pathologica Microbiologica Scandinavica, 2009
- The Effect of a Short Antibiotic Course in Transurethral Prostatic ResectionScandinavian Journal of Urology and Nephrology, 1984
- Short-term prophylaxis with cefotaxime for prostatic surgery.BMJ, 1982
- Concentrations of cefotaxime in serum, urine and tissues of urological patientsInfection, 1981
- TRIMETHOPRIM ALONEThe Lancet, 1980
- Systemic Antibiotics for Prophylaxis in Urologic Surgery: A Critical ReviewJournal of Urology, 1979
- Antimicrobial Prophylaxis in UrologyJournal of Urology, 1978
- Co-trimoxazole in prevention of bacteriuria after prostatectomy.BMJ, 1976
- Route and Prophylaxis of Ascending Bladder Infection in Male Patients with Indwelling CathetersJournal of Urology, 1972
- Urinary Tract Infections Following Transurethral Prostatectomy: With Special Reference to the Use of AntimicrobialsJournal of Urology, 1970