Experimental Allergic Neuritis in the Chicken
Open Access
- 1 September 1967
- journal article
- research article
- Published by SAGE Publications in Pathologia veterinaria
- Vol. 4 (5) , 464-476
- https://doi.org/10.1177/030098586700400503
Abstract
Experimental allergic neuritis was reproduced in chickens, by inoculation of chicken and guinea pig nerves in complete Freund's adjuvant. Paralysis was observed in a percentage of inoculated birds. Histopathologically this experimental autoimmune disease was characterized by severe demyelination of peripheral nerves in all experimental animals. In addition, oedema and/or lymphoid infiltration occurred in some of the animals. The similarity of experimental allergic neuritis to the inflammatory lesions of Marek's disease is stressed and the possible role of autoimmune processes in the pathogenesis of Marek's disease is discussed.Keywords
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