CRITICAL FLICKER FREQUENCY AFTER SMALL DOSES OF METHOHEXITONE, DIAZEPAM AND SODIUM 4-HYDROXYBUTYRATE
Open Access
- 1 February 1971
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 43 (2) , 110-112
- https://doi.org/10.1093/bja/43.2.110
Abstract
Statistically significant depression of critical flicker frequency has been measured following the intravenous injection of methohexitone (0.15 mg/kg), diazepam (0.05 mg/kg) and sodium 4-hydroxybutyrate (10 mg/kg). In the cases of methohexitone and diazepam the maximal measured changes (4.73 per cent and 7.07 per cent, respectively) occurred after 5 minutes and persisted for up to 90 minutes. After 4-hydroxybutyrate, depression was maximal at 15 minutes (4.32 per cent), but had disappeared by 30 minutes. No significant changes occurred after the injection of isotonic saline.Keywords
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