Effect of Certain Amino Acids and Peptides on Hyaluronidase Production by Staphylococcus aureus

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Abstract
S. aureus, strain SAB2, synthesized hyaluronidase in a chemically defined medium only in the presence of tyrosine and trypto-phan, even though these amino acids were not required for optimal growth. Glycine was indispensable for growth of this organism. Sup-plementation of the synthetic medium with glycyl-L-tyrosine or glycyl-L-tryptophan enhanced both growth and hyaluronidase production.