Pharmacogenetics of the human drug-transporter gene MDR1: impact of polymorphisms on pharmacotherapy
- 3 August 2001
- journal article
- review article
- Published by Elsevier in Drug Discovery Today
- Vol. 6 (16) , 835-839
- https://doi.org/10.1016/s1359-6446(01)01892-x
Abstract
No abstract availableKeywords
This publication has 42 references indexed in Scilit:
- A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutantsPublished by Elsevier ,2003
- A Family of Drug Transporters: the Multidrug Resistance-Associated ProteinsJNCI Journal of the National Cancer Institute, 2000
- p53 and P-glycoprotein expression are significant prognostic markers in advanced head and neck cancer treated with chemo/radiotherapyThe Journal of Pathology, 2000
- The prognostic significance of membrane transport-associated multidrug resistance (MDR) proteins in leukemiaInt. Journal of Clinical Pharmacology and Therapeutics, 2000
- Multidrug resistance mediated by the ATP-binding cassette transporter protein MRPBioEssays, 1998
- Evidence for two nonidentical drug-interaction sites in the human P-glycoproteinProceedings of the National Academy of Sciences, 1997
- Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell LineScience, 1992
- Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.Proceedings of the National Academy of Sciences, 1987
- Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cellsCell, 1986
- Isolation and expression of a complementary DNA that confers multidrug resistanceNature, 1986