Chapter 27. Application of Combinatorial and Parallel Synthesis to Medicinal Chemistry
- 1 January 1999
- book chapter
- Published by Elsevier
Abstract
No abstract availableThis publication has 88 references indexed in Scilit:
- Novel inhibitors of α4β1 integrin receptor interactions through library synthesis and screeningBioorganic & Medicinal Chemistry Letters, 1998
- Design of Novel, Potent, Noncovalent Inhibitors of Thrombin with Nonbasic P-1 Substructures: Rapid Structure−Activity Studies by Solid-Phase SynthesisJournal of Medicinal Chemistry, 1998
- High throughput purification methods in combinatorial solution phase synthesisDrugs of the Future, 1998
- New methods for obtaining high-resolution NMR spectra of solid-phase synthesis resins, natural products, and solution-state combinatorial chemistry librariesDrugs of the Future, 1998
- Synthesis and activity of 2,6,9-trisubstituted purinesBioorganic & Medicinal Chemistry Letters, 1997
- Solid-phase synthesis of a selective αvβ3 integrin antagonist libraryBioorganic & Medicinal Chemistry Letters, 1997
- Automated Synthesis and Purification of Amides: Exploitation of Automated Solid Phase Extraction in Organic SynthesisSynthesis, 1997
- Solid-phase parallel synthesis applied to lead optimization: Discovery of potent analogues of the GPIIb/IIIa antagonist RWJ-50042Bioorganic & Medicinal Chemistry Letters, 1996
- Solid phase organic synthesis (SPOS): A novel route to diketopiperazines and diketomorpholinesMolecular Diversity, 1996
- Diversity Profiling and Design Using 3D Pharmacophores: Pharmacophore-Derived Queries (PDQ)Journal of Chemical Information and Computer Sciences, 1996