Metabolic Functions of Thiamine and Lipoic Acid
- 1 October 1953
- journal article
- research article
- Published by American Physiological Society in Physiological Reviews
- Vol. 33 (4) , 544-559
- https://doi.org/10.1152/physrev.1953.33.4.544
Abstract
This is a review of current research on the metabolic functions of lipoic acid and thiamine not previously summarized. The topics discussed are: (1) the role of lipoic acid and thiamine in the oxidative decarboxylation of alpha-keto acids; (2) the role of thiamine in the generation and utilization of "active glycoal-dehyde" and; (3) a proposed role of lipoic acid in the light reactions of photosynthesis.Keywords
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