IMMUNE RESPONSES TO CANINE DISTEMPER VIRUS IN JOINT DISEASES OF DOGS

Abstract
Measurement of immune complexes, antibodies against canine distemper virus (CDV) and anti-CDV antibodies in immune complexes were made in sera and SF from ‘normal’ dogs and from dogs with joint diseases. These data were compared with cytological analyses of SF samples. In dogs with canine rheumatoid-like arthritis (CRA) there were correlations between circulating anti-CDV antibody levels and circulating immune complex levels (PPPP<0.001). The results demonstrated a relationship between CDV and ongoing synovial inflammation in dogs with CRA.

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