Improved parameter estimates in drug-protein binding studies by non-linear regression
- 1 October 1974
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 26 (10) , 807-813
- https://doi.org/10.1111/j.2042-7158.1974.tb09177.x
Abstract
A quantitative comparison of various methods of fundamental binding parameter estimation is presented. For optimal reliability, choice of a particular approach should be made on a critical assessment of the experimental procedure and various calculated statistical criteria, rather than on the ease of data treatment.Keywords
This publication has 9 references indexed in Scilit:
- Least squares: Linear and non-linearJournal of Chemical Education, 1973
- A computer analysis of drug-protein binding dataComputer Programs in Biomedicine, 1971
- Problems Associated with Analysis of Pharmacokinetic ModelsJournal of Pharmaceutical Sciences, 1971
- Interaction of Bishydroxycoumarin with Human Serum AlbuminJournal of Pharmaceutical Sciences, 1971
- The Binding of Drugs by Plasma ProteinsJournal of Pharmaceutical Sciences, 1968
- Multiplicity of Binding. Range of Validity and Practical Test of Adair's Equation*Biochemistry, 1965
- A Simplex Method for Function MinimizationThe Computer Journal, 1965
- THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONSAnnals of the New York Academy of Sciences, 1949
- The Binding of Organic Ions by Proteins1Journal of the American Chemical Society, 1946