Cleavage of Methyl and Benzyl Esters by Thiocyanate

1 January 1975

journal article
research article
Published by Taylor & Francis in Synthetic Communications

Vol. 5 (4) , 305-307
https://doi.org/10.1080/00397917508064126

Abstract

Growing attention is being accorded to nonsaponific cleavage of esters. Strong nucleophiles (LiI,¹ RS⁻, ²) have been exploited successfully to effect rupture of 0-alkyl bonds in methyl and a few other esters. As reagents of this sort are still quite limited, we felt that it may be of interest to provide some alternatives.

Keywords

NUCLEOPHILES
BENZYL ESTERS
CLEAVAGE
RUPTURE
THIOCYANATE GROWING
GROWING ATTENTION

This publication has 1 reference indexed in Scilit:

An improved reagent for the o-alkyl cleavage of methyl esters by nucleophilic displacement
Tetrahedron Letters, 1970