Bath-water compared with oral delivery of 8-methoxypsoralen PUVA therapy for chronic plaque psoriasis
- 1 October 1992
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 127 (4) , 392-395
- https://doi.org/10.1111/j.1365-2133.1992.tb00460.x
Abstract
Forty-four patients with chronic plaque psoriasis were randomly allocated to treatment with bath-water-delivered 8-methoxypsoralen (bath 8-MOP) or oral 8-methoxypsoralen (oral 8-MOP) PUVA therapy. There was a significant reduction in extent of the lesions and psoriasis area and severity index (PASI) after 20 treatments with each modality. There was a fourfold reduction in cumulative ultraviolet A (UVA) dose in the bath group. Side-effects of erythema and nausea were less with bath therapy.Keywords
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