Leukaemia-Associated Antigen (LAA) in Proliferative Blood Disorders

Abstract
Serum LAA was found in 41-75% of patients with acute leukemia or chronic myelogenous leukemia, but in only 12% of persons suffering from chronic lymphocytic leukemia. LAA was present in detectable amounts in 1% of healthy blood donors. Thus LAA is truly leukemia associated rather than leukemia specific. Occurrence of LAA in the serum of a leukemia patient may signal a serious turn of the disease.