Gas Chromatographic Parameters. I. Correlation Between Column Efficiency, Resolving Power, and Analysis Time

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Abstract
An analysis is made of the correlation between column efficiency, resolving power, and analysis time based on the quasi-linear relation between peak width and retention time that is commonly observed in gas chromatography. Two approaches are used. The first makes use of the straightforward relation that exists between resolving power and the effective plate number of gas chromatographic columns; it is shown that the variation of effective plate numbers with dead-time adjusted retention data can be described quite satisfactorily with the help of only two parameters, viz., the number of theoretical plates at infinite capacity, Ninf, and a time quality factor, tq. The second approach relates column resolving power directly to deadtime adjusted retention data, using only Ninf and tq as column parameters. It is shown that columns are characterized quite well by these two parameters, Ninf being a measure of the maximum resolving power attainable and tq providing a measure of the decrease of column resolving power with decreasing retention. On the basis of the equations derived, a much more rational choice of columns and operating conditions becomes possible.

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