Electroretinographic Manifestations of Hyperbaric Oxygen

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Abstract
Recent advances in the use of hyperbaric oxygen in clinical medicine have renewed interest in the early manifestations of toxic effects of oxygen. The toxic effects on the lung and the brain have been well recognized but only few of the manifestations in the visual system have been defined and investigated. Subjective visual impairment was noted by Behnke.1 Beehler2 and Comroe3 reported ocular hypotonia and irritation of the iris as well as of the conjunctiva. Retinal injury following 40 hours of exposure to 100% oxygen has been described by Noell4 as marked reduction in size of the outer nuclear layer. Noell also found significant attenuation of the b-wave of the electroretinogram in animals exposed to one atmosphere of oxygen for 25 to 36 hours. Beehler2 observed reversible retinal detachment in dogs exposed to one atmosphere of 100% oxygen for three days. The purpose of the

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