Activated Protein C Resistance, Factor V Leiden, and Central Retinal Vein Occlusion in Young Adults

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Abstract
CENTRAL RETINAL vein occlusion (CRVO) is usually found among older patients and is usually associated with systemic vascular disease.1 Central retinal vein occlusion in younger patients is an uncommon finding; 7.5% to 19.8% of CRVOs have been reported to occur in patients younger than 50 years, but these rates may be overestimated as the younger adult who develops a CRVO is more likely to be referred to a retinal specialist because of the rarity of the condition.2,3 Associated medical conditions in the young adult who experiences a CRVO may include hypertension,4 hyperlipidemia,4 migraine,5 carotid artery disease,6 or hypercoagulability.5 However, identifiable associated medical disease is less common than that found in the older adult population in whom CRVO develops.2,3