High-Density Lipoprotein Cholesterol and Ischemic Stroke in the Elderly
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Open Access
- 6 June 2001
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 285 (21) , 2729-2735
- https://doi.org/10.1001/jama.285.21.2729
Abstract
Stroke is a major cause of death and disability in the United States and is a growing public health concern. The latest projections estimate that more than 1 million strokes will occur every year by the year 2010. Moreover, stroke has a disproportionate impact on elderly, black, and Hispanic persons, who are among the fastest growing segments of the US population. Many studies have provided strong evidence for lipids as a risk factor for coronary artery disease (CAD). These studies demonstrate a direct relationship between total cholesterol, low-density lipoprotein cholesterol (LDL-C), and CAD and an inverse relationship between high-density lipoprotein cholesterol (HDL-C) and CAD.1-4 These relationships have not been as clearly established for ischemic stroke with some studies even questioning whether cholesterol is a risk factor for stroke.Keywords
This publication has 1 reference indexed in Scilit:
- Alcohol-induced changes in serum lipoproteins and in their metabolismAmerican Heart Journal, 1987