Numbers of Receptor Sites from Scatchard Graphs: Facts and Fantasies
- 24 September 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 217 (4566) , 1247-1249
- https://doi.org/10.1126/science.6287580
Abstract
Data for ligand and receptor binding presented in the format of a Scatchard graph are compared with the same data shown as bound ligand plotted against the logarithm of free ligand. From this comparison it is apparent that extrapolations in the Scatchard graph to yield total number of receptor sites are generally not correct.This publication has 9 references indexed in Scilit:
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