STREPTOMYCIN IN SURGICAL INFECTIONS. VII. NONPULMONARY TUBERCULOSIS (LYMPH NODES, URINARY TRACT, BONE, AND PERITONEUM)

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Abstract
This report embraces the results of experiences with streptomycin therapy in 121 cases of nonpulmonary tuberculosis. In 35 cases of tuberculous lymphadenitis, streptomycin therapy was better and more prompt when combined with surgery. The ideal treatment appears to be the admn. of therapeutic levels for 1-2 mos. If no response is obtained then surgery is sometimes necessary. Following surgery, the same therapeutic levels are maintained until primary healing is accomplished. One failure was attributed to streptomycin-fastness of the organism, another to streptomycin toxicity. In 46 cases of tuberculosis of the genito-urinary tract only 11 improved on streptomycin therapy. The 24 cases of tuberculosis of various bones are too small to warrant positive conclusions but indicate that the drug can influence favorably the equilibrium between soft tissue defenses and sinus tract formations. The series demonstrates that streptomycin is a useful umbrella for surgery of tuberculous lesions. 17 cases of tuberculous peritonitis were very ill when streptomycin was begun. 11 patients showed marked improvement; 2 patients died.

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