Hypoprothrombinemia Associated with Cefoperazone Treatment

1 April 1984

journal article
case report
Published by SAGE Publications in Drug Intelligence & Clinical Pharmacy

Vol. 18 (4) , 314-316
https://doi.org/10.1177/106002808401800410

Abstract

A patient with acute renal failure and gram-negative septicemia developed hypoprothrombinemia during treatment with cefoperazone. The coagulation defect was corrected by vitamin K administration. A multifactorial pathogenetic mechanism of vitamin K deficiency that developed during treatment with parenteral antibiotics is presented.

Keywords

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