Clinical and Serological Evaluation of a Meningococcal Polysaccharide Vaccine Groups A, C, Y, and W135

Abstract
The clinical (human) evaluation of a meningococcal polysaccharide vaccine containing groups A, C, Y and W135 antigens was described. The vaccine was found to be clinically acceptable and a significant antibody response was detected by both a bactericidal assay and a solid-phase radioimmune assay.

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