The Antibacterial Effect of Selected Neuroleptics on Vibrio Cholerae
- 31 August 1985
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Series B: Microbiology
- Vol. 93B (1-6) , 49-51
- https://doi.org/10.1111/j.1699-0463.1985.tb02850.x
Abstract
The present investigation was undertaken to illustrate the antibacterial effect of chloropromazine, clopenthixol and levomepromazine-maleate. Clopenthixol had the strongest antibacterial effect. It is known that chlorpromazine also has an antisecretory activity. The fact that clopenthixol exists in cis(Z)- and trans(E)-isomerical compounds, and that these compounds both have an antibacterial effect, but only the cis-compound has an antisecretory and neuroleptic effect, might suggest the development of more specific pharmaceuticals in these new fields.Keywords
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