Photochehical Fluorimetric Determination of Primaquine in a Flowing Solvent with Application to Blood Serum
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Analytical Letters
- Vol. 17 (16) , 1831-1841
- https://doi.org/10.1080/00032718408077186
Abstract
Primaquine in a flowing solvent is photolyzed with a 200 W Xe-Hg arc lamp and the intensely fluorescent photochemical product is measured in a fluorimeter. The effect of solvent composition and pH, irradiation time, and excitation conditions are evaluated. Primaquine in blood serum is measured by introducing a sample of blood serum into the flowing stream and performing the photochemical-fluorescence measurement. The fluorescence background of blood serum was very low allowing a detection limit of less than 0.1 μg/mL. Excellent recoveries were obtained.Keywords
This publication has 8 references indexed in Scilit:
- Photochemical analysis studies—III A fluorimetric and ultraviolet spectrophotometric study of the photolysis of chloroquine on silica-gel thin layers, and its analytical applicationTalanta, 1982
- Spectrophotometric determination of primaquine phosphate in pharmaceutical preparationsThe Analyst, 1980
- Gas chromatography mass spectrometry studies on biologically important 8-aminoquinoline derivativesJournal of Mass Spectrometry, 1978
- A Quantitative Photochemical-Fluorimetric Method for Measurement of Nonfluorescent Vitamin K1Applied Spectroscopy, 1976
- Assay of Pharmaceuticals Using Quantitative Thin-Layer Chromatography-Elution TechniquesJournal of Chromatographic Science, 1975
- EFFECTS OF PRIMAQUINE AND OTHER RELATED COMPOUNDS ON THE RED BLOOD CELL MEMBRANE. I. NA+ AND K+ PERMEABILITY IN NORMAL HUMAN CELLS*Journal of Clinical Investigation, 1961
- A FLUOROMETRIC METHOD FOR THE DETERMINATION OF PAMAQUINE, SN-13276, AND SN-3294Journal of Biological Chemistry, 1948