Type III Secretion: More Systems Than You Think
Open Access
- 1 October 2005
- journal article
- review article
- Published by American Physiological Society in Physiology
- Vol. 20 (5) , 326-339
- https://doi.org/10.1152/physiol.00011.2005
Abstract
The type III secretion (T3S) pathway allows bacteria to inject effector proteins into the cytosol of target animal or plant cells. T3S systems evolved into seven families that were distributed among Gram-negative bacteria by horizontal gene transfer. There are probably a few hundred effectors interfering with control and signaling in eukaryotic cells and offering a wealth of new tools to cell biologists.Keywords
This publication has 145 references indexed in Scilit:
- Bioinformatics, genomics and evolution of non-flagellar type-III secretion systems: a Darwinian perpectiveFEMS Microbiology Reviews, 2005
- Cysteine proteases in phytopathogenic bacteria: identification of plant targets and activation of innate immunityCurrent Opinion in Plant Biology, 2004
- The versatile bacterial type IV secretion systemsNature Reviews Microbiology, 2003
- The Yersinia Ysc–Yop 'Type III' weaponryNature Reviews Molecular Cell Biology, 2002
- Genome sequence of Yersinia pestis, the causative agent of plagueNature, 2001
- Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unitJournal of Molecular Biology, 2001
- Flagellin polymerisation control by a cytosolic export chaperoneJournal of Molecular Biology, 2001
- Chromobacterium violaceum: A Review of Pharmacological and Industiral PerspectivesCritical Reviews in Microbiology, 2001
- Contribution of Salmonella typhimurium type III secretion components to needle complex formationProceedings of the National Academy of Sciences, 2000
- The many facets of melioidosisTrends in Microbiology, 1999