THE ELECTROCARDIOGRAM IN ADDISONʼS DISEASE

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Abstract
In 90 patients with diagnosis of Addison''s disease, 40 male and 50 female, ages 9-65 yrs., the ecg. was normal in 48%, abnormal in 52%. Abnormalities were non-specific and unaffected by DOCA. No specific abnormalities were noted in patients in crisis. Cortisone had no effect on normal ecg. in patients with Addison''s disease, but where an abnormal ecg. was present prior to treatment, it reverted toward normal in 10 of 12 patients. In 2 of these cases when Cortisone was discontinued, omission of Cortisone resulted in return of tracing toward abnormal control configuration. Anatomical findings in 5 fatal cases are discussed.