ANTIGEN-INDUCED LYMPHOBLAST TRANSFORMATION IN THE DIAGNOSIS OF COW'S MILK ALLERGIC DISEASES IN INFANCY AND EARLY CHILDHOOD
- 1 April 1974
- Vol. 30 (1) , 34-42
- https://doi.org/10.1111/j.1398-9995.1974.tb02694.x
Abstract
The in vitro lymphocyte stimulation of 17 milk-allergic and 8 control children was carried out with .beta.-lactoglobulin, bovine serum albumin (BSA), bovine hair extract and phytohemagglutinin (PHA). The blastic transformation was significant with at least 1 of the milk antigens in 15 of the patients, but in only 1 of the controls. In 2 cases, corresponding to milk allergy of Arthus type (Schoenlein-Henoch purpura and Heiner pneumonitis), a high ratio of specific lymphocyte blast transformation was observed and the cellular reaction to PHA was pathologically decreased. A significant correlation could be demonstrated between the degrees of blastic transformation to BSA and bovine hair extract.This publication has 14 references indexed in Scilit:
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