A FATAL CASE OF FARMERS LUNG - A STUDY OF SPECIFIC ANTIBODY CLASSES IN THE SERUM AND ALVEOLAR-LAVAGE

  • 1 January 1985
    • journal article
    • research article
    • Vol. 2  (1) , 11-14
Abstract
A 61 year old agricultural worker, without any respiratory past history, presented with a pulmonary fibrosis of rapid and fatal outcome. This was due to an extrinsic allergic fibrosing alveolitis of the Farmer''s lung type. A search for percipitants vis-a-vis Micropolyspora faeni was strongly positive in the serum and broncho-alveolar lavage. Specific IgA antibodies to M. faeni, as well as specific antigenic fractions of M. faeni were demonstrated in the broncho-alveolar lavage. This IgA was almost certainly produced locally.

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