Nuclear magnetic resonance study of the conformations of penicillins in solution using lanthanide ion probes
- 1 January 1975
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Faraday Transactions 2: Molecular and Chemical Physics
- Vol. 71, 1145-1153
- https://doi.org/10.1039/f29757101145
Abstract
The conformations of ampicillin, penicillin G and penicillin V sulphoxide in aqueous solution have been studied by analysing the shift and relaxation perturbations to the nuclear magnetic resonance spectra induced by binding lanthanide cations. The conformations of the molecules in solution are very similar, despite differences observed in the solid state.Keywords
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