Immunotherapy Experiments With a Methylcholanthrene-Induced Guinea Pig Liposarcoma2

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Abstract
Intradermal immunization of syngeneic guinea pigs with a methylcholanthrene-induced liposarcoma effectively prevented the growth of an intramuscular tumor challenge when immunization was initiated at the same time as, or up to 10 days after, challenge. The most effective immunogens for intradermal immunization were viable cells from grafts of the transplanted tumor, but irradiated tumor cells and tumor cells grown in tissue culture were also effective.

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