Transition-state stabilization by adenosine deaminase: structural studies of its inhibitory complex with deoxycoformycin
- 8 April 1986
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 25 (7) , 1616-1621
- https://doi.org/10.1021/bi00355a025
Abstract
Note: In lieu of an abstract, this is the article's first page.This publication has 15 references indexed in Scilit:
- Total synthesis of (8R)-3-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol (pentostatin), the potent inhibitor of adenosine deaminaseThe Journal of Organic Chemistry, 1982
- Synthesis of [8-3H]PentostatinJournal of Labelled Compounds and Radiopharmaceuticals, 1981
- Adenosine deaminase and adenylate deaminase: comparative kinetic studies with transition state and ground state analog inhibitorsBiochemistry, 1980
- Adenylate deaminase: Potent inhibition by 2′-deoxycoformycin 5′-phosphateBiochemical and Biophysical Research Communications, 1979
- Influence of substituent ribose on transition state affinity in reactions catalyzed by adenosine deaminaseBiochemistry, 1977
- Thiohemiacetal formation by inhibitory aldehydes at the active site of papainBiochemistry, 1977
- Tight-binding inhibitors—IV. Inhibition of adenosine deaminases by various inhibitorsBiochemical Pharmacology, 1977
- Purification of human erythrocyte adenosine deaminase by affinity column chromatography.Journal of Biological Chemistry, 1976
- SUBSTRATE BINDING BY ADENOSINE DEAMINASE - SPECIFICITY PH DEPENDENCE AND COMPETITION BY MERCURIALS1967
- Mechanisms Related to Enzyme CatalysisPublished by Wiley ,1962