Abstract
The author describes 2 cases of a disease supposed to be hitherto unknown, in which the patients, aged 16 and 18 yrs., resp., showed enlargement of 1 of the long bones of either the hand or foot, with swelling and considerable pain. X-ray showed increased volume of the bone, with a thinning of the shadow in the most enlarged end of the diaphysis in one case. Histopatho-logical examination after operation revealed a bony new-growth which was neither a tumor nor an inflammatory process, originating from a focus corresponding to the thinning of the diaphysis; it was built up of a central, amorphous, collagenous substance surrounded by a highly vascularized zone of spongy bone from which vessels and osteoblasts penetrated into the central mass. The author concludes that the process is apparently of embryonic origin.

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