The Effect of a ‘Sucrose-Free’ Diet on Oral Glucose Tolerance in Man

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Abstract
(1) 19 members of an Antarctic expedition were fed on a diet in which sucrose was replaced by glucose and calcium cyclamate for 14 weeks. Oral glucose tolerance tests were carried out whilst on this diet and for a comparable period of time when on the normal base diet. (2) Changes in body weight were small and not significant. (3) Although blood glucose levels were significantly lower 0.5 h after ingestion of the glucose load on the ‘sucrose-free’ diet towards the end of the diet period, compared with values obtained on the normal base diet, this change was reversed at 1 and 1.5 h after ingestion of the glucose load. (4) It is concluded that there is a small but significant change in glucose tolerance after nine weeks on a ‘sucrose-free’ diet.

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