Accelerated Development of Malignant Lymphomas in AKR Mice Injected at Birth with 7,12-Dimethylbenz(a) Anthracene.
- 1 August 1962
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 110 (4) , 881-884
- https://doi.org/10.3181/00379727-110-27680
Abstract
Subcutaneous injection of 100 [mu]g of 7, 12-dimethyl-benz(a) anthracene in 0.05 ml tri-n-caprylin in newborn AKR mice considerably shortened the latent period of malignant lymphomas. All malignant lymphomas observed in the treated group before the time of appearance of the first lymphoma in the controls were of the stem-cell type.Keywords
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