Effect of lithium administration on RNA metabolism in rat brain
- 1 May 1971
- journal article
- research article
- Published by Cambridge University Press (CUP) in Psychological Medicine
- Vol. 1 (3) , 254-259
- https://doi.org/10.1017/s003329170004188x
Abstract
SYNOPSIS: An attempt has been made to explain the changes in uric acid levels observed in the phase of manic depressive illness by suggesting that they may be a reflection of changes in brain RNA metabolism. The effect of prolonged lithium administration on RNA synthesis in rat brain and liver has been studied. Differences in the rate of turnover of brain RNA between the lithium-treated and saline control animals have been observed.Keywords
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