Synthesis of 2-(p-Trifluoroacetamidophenyl)ethylO-β-D-Mannopyranosyl-(l→2)-O-α-D-Mannopyranosyl-(l→2)-O-[α-D-Glucopyranosyl-(1→3)]-O-α-D-Mannopyranosyl-(1→2)-O-β-D-Manpopyranosyl-(1→3)-2-Acetamido-2-Deoxy-β-D-Gluco-Pyranoside, Corresponding to the Repeating Unit of theSalmonella Thompson, Serogroup C1O-Antigen Lipopolysaccharide, and of a Pentasaccharide Fragment Thereof

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Abstract
2-(p-Trifluoroacetamidophenyl)ethyl O-β-D-mannopyranosyl-(l→2)-O-α-D-mannopyranosyl-(1→2)-O-[α-D-glucopyranosyl-(1→3)]-O-α-D-manno-pyranosyl-(1→2)-O-β-D-mannopyranosyl-(l→3)-2-acetamido-2-deoxy-β-D-glucopyranoside was synthesized. The main glycosylation method used was activation of thioglycosides with either dimethyl(methylthio)sulfonium triflate (DMTST), N-iodosuccinimide (NIS)/silver triflate or iodonium dicollidine perchlorate (IDCP).