THE EFFECT OF PARATHYROID HORMONE ON PHOSPHATE EXCRETION IN THE RAT

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Abstract
The magnitude of the decrease in serum inorganic phosphate and the increase in urine phosphate of parathyroidectomized rats caused by injected parathyroid hormone has been studied. About 3 u.s.p. units of this hormone have been found to cause maximum changes in both serum and urine phosphate. Both responses depend on the respective initial phosphate level. Urine phosphate levels too high for more than minimal changes in phosphate excretion have been reduced by diets containing aluminium sulphate.

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